Oxidative Stress and Inflammation

Inflammation, Oxidative Stress, and Obesity

Obesity is a chronic disease of multifactorial origin and can be defined as an increase in the accumulation of body fat. Adipose tissue is not only a triglyceride storage organ, but studies have shown the role of white adipose tissue as a producer of certain bioactive substances called adipokines. Among adipokines, we find some inflammatory functions, such as Interleukin-6 (IL-6); other adipoki...

Atherosclerosis, Inflammation and Oxidative Stress

Atherosclerosis is a focal disease of the arterial wall that leads to cardiovascular disease (CVD), the biggest cause of morbidity and mortality in Western societies. CVD, a group of disorders of the heart and the vasculature, includes atherosclerosis, high blood pressure, coronary heart disease, congestive heart failure, stroke and congenital heart defects. The World Health Organization report...

Oxidative Stress, Inflammation

In the Sabra rat, oxidative stress (OS) and inflammation precede the development of hypertension. Inhibition of the phagocytic NADPH oxidase attenuates the rise in blood pressure. The present study was set to identify possible priming agents for this enzyme and to test the hypothesis that the phagocytic NADPH oxidase contributes to OS and inflammation. Sabra salt-sensitive and Sabra salt-resist...

Lung Inflammation, Oxidative Stress and Air Pollution

Statins, inflammation, oxidative stress, and atrial fibrillation.

In this issue of the Journal, Negi et al.1 reported their study investigating whether or not high-dose atorvastatin could reduce atrial fibrillation (AF) recurrence after electrical cardioversion (EC) by modifying systemic oxidative stress and inflammation. They concluded that while high-dose atorvastatin could reduce selective markers of inflammation, it did not affect systemic oxidative stres...